Zakynthos Airport Airlines
| Airlines | Destinations |
| Austrian Airlines | Seasonal: Vienna Seasonal charter: Linz |
| Belavia | Seasonal charter: Minsk |
| Aviolet | Seasonal charter: Belgrade |
| Blue Panorama Airlines | Seasonal: Bergamo airport, Bologna, Milan–Malpensa, Rome airport Fiumicino |
| Blue Air | Seasonal: Bucharest, Timișoara |
| British Airways | Seasonal: London–Heathrow |
| Brussels Airlines | Seasonal: Brussels |
| Condor | Seasonal: Düsseldorf, Frankfurt, Hamburg, Munich |
| Corendon Dutch Airlines | Seasonal: Amsterdam airport, Maastricht/Aachen |
| Danish Air Transport | Seasonal charter: Aarhus, Billund |
| easyJet | Seasonal: Bristol, Liverpool, London–Gatwick, London–Stansted, Milan–Malpensa airport |
| Edelweiss Air | Seasonal: Zürich |
| Enter Air | Seasonal charter: Katowice, Poznań, Vilnius, Warsaw–Chopin,Wrocław |
| Eurowings | Seasonal: Düsseldorf, Stuttgart |
| Finnair | Seasonal: Helsinki |
| Jet2.com | Seasonal: Belfast–International, Birmingham, East Midlands, Edinburgh, Glasgow, Leeds/Bradford, London–Stansted, Manchester, Newcastle upon Tyne |
| Laudamotion | Seasonal: Vienna |
| Lufthansa | Seasonal: Munich (begins 4 April 2020) |
| NordStar | Seasonal charter: Moscow–Domodedovo |
| Novair | Seasonal charter: Gothenburg, Oslo–Gardermoen, Stockholm–Arlanda |
| Olympic Air | Athens |
| Ryanair | Seasonal: Bergamo, Bologna (begins 1 May 2020) |
| Ryanair Sun | Seasonal charter: Katowice Warsaw–Chopin, Wrocław |
| Sky Express | Athens, Kefalonia |
| SkyUp | Seasonal charter: Kiev–Boryspil (begins 31 May 2020) |
| Smartwings | Seasonal: Brno, Ostrava, Prague airport |
| Smartwings Hungary | Seasonal: Budapest, Debrecen |
| Smartwings Poland | Seasonal charter: Katowice, Poznań, Warsaw–Chopin |
| Smartwings Slovakia | Seasonal: Bratislava |
| Swiss International Air Lines | Seasonal: Geneva |
| TAROM | Seasonal charter: Bucharest, Cluj-Napoca |
| Transavia | Seasonal: Amsterdam, Eindhoven |
| Transavia France | Seasonal: Paris airport – Orly |
| TUI Airways | Seasonal: Birmingham, Bournemouth (begins 3 May 2020), Bristol, Cardiff, Doncaster/Sheffield, East Midlands, Exeter, Glasgow, London–Gatwick, London–Luton, London–Stansted, Manchester, Newcastle upon Tyne Seasonal charter: Dublin |
| TUI fly Belgium | Seasonal: Brussels |
| TUI fly Netherlands | Seasonal: Amsterdam, Rotterdam/The Hague |
| TUI fly Nordic | Seasonal charter: Copenhagen, Helsinki, Oslo–Gardermoen, Stockholm–Arlanda |
| Volotea | Seasonal: Bari airport , Naples airport, Palermo airport, Venice, Verona |
| Vueling | Seasonal: Rome airport Fiumicino |
| Wizz Air | Seasonal: Budapest |
| Expected* | Alicante Airport ALC Spain, Barcelona Airport BCN, Madrid Airport MAD |
| Expected 2022 | Palma Airport PMI |